Also, PP242 was demonstrated to induce ERK activation in MM cell lines in addition to Main cells, which wasn't correlated with S6K inhibition nor was it prevented by PI3K inhibition. ERK activation is often prevented by MEK inhibitors and is particularly linked to concurrent stimulation of Raf kinase action although https://rosthornina02356.wssblogs.com/28565463/what-does-e7449-mean