Gastrointestinal (GI): NSAIDs that block COX-1 action have correlations with GI problems due to the inhibition in the synthesis of gastroprotective agents which include PGE2 and also other prostaglandins. This inhibition results in reduced mucin generation by gastric epithelial cells, less bicarbonate secretion, and less epithelial cell turnover, amongst other https://stephens495syz2.gynoblog.com/profile