Butabarbital will decrease the extent or impact of fedratinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Keep away from or Use Alternate Drug. Impact of coadministering a strong CYP3A4 inducer with fedratinib has not been examined. butabarbital will lower the extent or result of pioglitazone by affecting hepatic/intestinal enzyme CYP3A4 metabolism. https://andreij952zwt4.activablog.com/profile