Exploration into conolidine has led to discovery of the opioid receptor in your body referred to as ACKR3/CXCR7. ACKR3 appears to be quite possibly the most sought after target for conolidine, which also disregards the opposite 4 classical opioid receptors(three). Conolidine has become found in the tabernaemontana divaricata plant, https://www.proleviate.com/post/conolidine-an-alternative-natural-pain-relief-to-replace-traditional-painkillers