Investigate into conolidine has brought about discovery of the opioid receptor in the human body named ACKR3/CXCR7. ACKR3 seems to be essentially the most sought after focus on for conolidine, which also disregards the other 4 classical opioid receptors(three). Conolidine has long been present in the tabernaemontana divaricata plant, https://johsocial.com/story11446234/5-simple-techniques-for-conolidin-to-replace-traditional-painkillers